Gertrude Belle Elion

Gertrude Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, and a 1988 recipient of the Nobel Prize in Physiology or Medicine. Working alone as well as with George H. Hitchings, Elion developed a multitude of new drugs, using innovative research methods that would later lead to the development of the AIDS drug AZT. Rather than relying on trial-and-error, Elion and Hitchings used the differences in biochemistry between normal human cells and pathogens (disease-causing agents) to design drugs that could kill or inhabit the reproduction of particular pathogens without harming the host cells.